Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Constipation
ADR ID BADD_A01059
ADR Hierarchy
07      Gastrointestinal disorders
07.02      Gastrointestinal motility and defaecation conditions
07.02.02      Gastrointestinal atonic and hypomotility disorders NEC
07.02.02.001      Constipation
Description A disorder characterized by irregular and infrequent or difficult evacuation of the bowels. [CTCAE] Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections. | Difficult defecation. | Symptom characterized by the passage of stool once a week or less. [MeSH]
MedDRA Code 10010774
MeSH ID D003248
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Constipation | Constipation (excl faecal impaction) | Iatrogenic constipation | Obstipation | Constipation aggravated | Constipation (excl fecal impaction) | Stools absent | Constipation chronic | Opioid induced constipation | Slow transit constipation | Chronic idiopathic constipation | Absent bowel movement | Habitual constipation | Dyschezia | Colonic Inertia
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01799Ponatinib0.001690%
BADD_D01800Ponatinib hydrochloride--
BADD_D01802Porfimer--
BADD_D01803Porfimer sodium--
BADD_D01804Posaconazole--
BADD_D01809Potassium chloride--
BADD_D01814Pralatrexate--
BADD_D01817Pramipexole0.000909%
BADD_D01818Pramipexole dihydrochloride--
BADD_D01824Pravastatin--
BADD_D01825Pravastatin sodium--
BADD_D01827Prazosin--
BADD_D01828Prazosin hydrochloride--
BADD_D01833Prednisolone sodium phosphate--
BADD_D01834Prednisone--
BADD_D01835Pregabalin--
BADD_D01842Procainamide--
BADD_D01846Procarbazine0.006335%
BADD_D01847Procarbazine hydrochloride--
BADD_D01848Prochlorperazine--
BADD_D01849Prochlorperazine edisylate--
BADD_D01850Prochlorperazine maleate--
BADD_D01851Procyclidine hydrochloride--
BADD_D01852Progesterone--
BADD_D01854Promethazine0.000077%
BADD_D01856Propafenone0.000627%
BADD_D01857Propafenone hydrochloride--
BADD_D01860Propantheline--
BADD_D01861Propantheline bromide--
BADD_D01865Propoxyphene--
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